USB device security is very important and most information centers including datacenters are blocking the use of USB inside their premises. However that cannot prevent wireless hacking fundamentally.
There can be various types of wireless hacking chips that can break the USB device security aforementioned. For ex., if a spy chip is implanted in a keyboard and controlled wirelessly ad remotely from outside, no one would know when and how it connects to the server for hacking.
Spy chip’s size is as small as a rice bead, so it can be hidden in a mouse, keyboard, processing board, or LAN cable connector for hacking inside the internal network.